Alternariol monomethyl ether （9-methoxy)

Alternariol monomethyl ether (AME), also known as 9-methoxyalternariol, is a mycotoxin, a toxic compound produced by certain types of fungi, particularly Alternaria species. It is closely related to alternariol, which is also produced by these fungi.

AME is commonly found in grains, such as wheat and barley, and in fruits, such as apples and grapes. It is considered a potential human carcinogen and has been linked to liver damage and other health effects. The toxic effects of AME are thought to be due to its ability to cause oxidative stress and DNA damage, leading to cellular damage and cell death.

To reduce the risk of exposure to AME, it is recommended to avoid consuming moldy or contaminated food products. Proper storage and handling of food products can also help to prevent fungal growth and mycotoxin production. Testing for AME levels in food products is also performed by regulatory agencies to ensure safety for human consumption.

In addition to the potential health risks to humans, AME can also have a negative impact on animal health and productivity. Therefore, it is important to monitor and control AME levels in animal feed as well.