Fumonisin B1

Fumonisin B1 is a mycotoxin, a toxic compound produced by certain types of fungi, particularly the fungus Fusarium verticillioides. It is commonly found in corn and corn-based food products, as well as in other grains such as rice and wheat.

Fumonisin B1 is considered a potential human carcinogen and has been linked to liver and kidney damage, as well as neural tube defects in animals. The toxic effects of fumonisin B1 are thought to be due to its ability to inhibit sphingolipid biosynthesis, which can lead to disruption of cell membrane function and cell death.

To reduce the risk of exposure to fumonisin B1, it is recommended to avoid consuming moldy or contaminated grains and grain-based products. Additionally, proper storage and handling of grains can help to prevent fungal growth and mycotoxin production. Testing for fumonisin B1 levels in food products is also performed by regulatory agencies to ensure safety for human consumption.